Male to female transsexuals using hormones

HRT causes a reduction in muscle mass and distribution towards female proportions. Milk discharge from the nipples can be a sign of elevated prolactin levels. Many pre-operative transgender women wait until after reassignment surgery to begin an active sex life. Male Reproductive Health and Dysfunction. Relative contraindications — in which the benefits of HRT may outweigh the risks, but caution should be used — include:. This is especially likely with hair growth from previously bald areas. It has been suggested that progestins be added during the last week of each cycle of estrogen therapy in order to develop more rounded breasts rather than the conical breasts many of these patients develop, but we have been unable to detect any difference in breast contour with or without progestins.

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Transgender hormone therapy (male-to-female)


Reproductive endocrinology, infertility, and contraception. Numerous other progestogens and by extension antigonadotropins have been used to suppress testosterone levels in men and are likely useful for such purposes in transgender women as well. During puberty, the voice deepens in pitch and becomes more resonant. In addition, they stimulate sex drive and the frequency of spontaneous erections and are responsible for acne, body odor, and scalp hair loss. Both estrogen and testosterone help to stimulate bone formation, especially during puberty. The distribution of adipose fat tissue changes slowly over months and years.

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Mishell; Val Davajan In spite of the induction of breast development, transgender women who undergo HRT do not have an increased risk of breast cancer. The water retention and subsequent swelling of breast tissue during this phase of the menstrual cycle are thought to be due to high levels of circulating progesterone stimulating the secretory cells of the breast. Progesterone is most commonly taken orally. Spironolactone is an antimineralocorticoid antagonist of the mineralocorticoid receptor and potassium-sparing diuretic , which is mainly used to treat high blood pressure , edema , high aldosterone levels , and low potassium levels caused by other diuretics , among other uses. It cannot undo many of the changes produced by naturally occurring puberty , which may necessitate surgery and other treatments to reverse see below. An assessment of the risks and benefits".

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